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M9630731.TXT
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1996-02-27
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Document 0731
DOCN M9630731
TI [Detection of HIV virus antibodies in saliva]
DT 9603
AU Bruckova M; Stankova M; Centrum AIDS, Infekcni klinika 1. lekarske
fakulty; Univerzity Karlovy, Fakultni nemocnice na Bulovce, Praha.
SO Epidemiol Mikrobiol Imunol. 1995 Sep;44(3):127-9. Unique Identifier :
AIDSLINE MED/96084472
AB The authors evaluate the use of saliva as alternative biological
material for detection of HIV antibodies. If collected properly and when
using the appropriate ELISA methods, HIV antibodies can be assessed in
saliva with considerable sensitivity and specificity. Testing in saliva
eliminates many disadvantages found when assessing HIV antibodies in
serum. It does not require trained staff for blood sampling, collection
and processing of saliva reduces the risk of professional infection to a
minimum and can be carried out also under field conditions. A great
advantage is the easy and unpretentious transport of collected samples
to the laboratory, even long distance transport at extreme temperatures
(transport medium in the testing kit Omni-SAL ensures great stability of
the sample as well as proper collection of the sample). Alternative
testing in saliva is useful in particular for epidemiological
surveillance and for screening of HIV antibodies in population groups
with a high risk of infections such as drug users and commercial works
where it is often very difficult to obtain blood samples for
examination.
DE English Abstract Enzyme-Linked Immunosorbent Assay Human HIV
Antibodies/*ANALYSIS Saliva/*VIROLOGY Sensitivity and Specificity
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).